The topic you choose must have enough depth that you can create a lot of content for it. This is important for building an authoritative site, for search engine optimization, and most importantly, for the end user. If you don't have enough content about a topic, you're not going to be taken very seriously as an authority on the topic and it's unlikely you can convince someone to make a purchase from you. 
A year ago, when I ran an ABestWeb contest for the best definition of affiliate marketing, Chris, who ended up winning the first prize, summarized things both eloquently and beautifully. He defined affiliate marketing as “the art of doing a merchant’s marketing better than they can, and profiting from it.” Many successful affiliates (also known as super affiliates) are truly better experts in what they do that most of the merchants that they promote. Consequently, they can market e-tailers’ products/services in such a way that merchants get incremental business, while they themselves make a good living off the per sale commission they get.

“I didn’t realize how much we were missing from not having an online presence until I started working with the SEO firm Brick Marketing. The Brick Marketing team took the time to guide us through the SEO process and helped bring our company into the online world. We’ve seen unbelievable success with our new website & owe much of our online lead generation to Brick Marketing’s efforts.”
One thing you should strongly consider is promoting digital information products. These products are attractive for two reasons. First, they have higher conversion rates because the customers can get instant access and instant gratification when they purchase. Second, they typically offer much higher commission rates than physical products -- which means more profits for you.
I built several small sites that only sell ‘small’ items for sale on Amazon. Typically $4/$5 an item, and items that are usually bought in bulk. Painting supplies, for instance. I then take out a small Facebook ad at the start of the month promoting that site. Usually 2 or 3 orders of multiple products is enough to send my commision percentage up, then it’ll stay that way until the end of the month. Hope that helps someone. 🙂
Since the emergence of affiliate marketing, there has been little control over affiliate activity. Unscrupulous affiliates have used spam, false advertising, forced clicks (to get tracking cookies set on users' computers), adware, and other methods to drive traffic to their sponsors. Although many affiliate programs have terms of service that contain rules against spam, this marketing method has historically proven to attract abuse from spammers.

Okay, I’ll be honest, when I first started out, I found it surprisingly difficult to understand how to even generate links (and deep links). For a while, I legitimately thought I was stupid. In hindsight, stupidity may have been a small part of the cause, but the truth is the process is actually pretty confusing. SO, I’ve written some pretty boring (though helpful) step-by-steps on how to generate links on a few common programs and affiliate networks… So, for my fellow life-dummies, here’s:
Once you've protected your prospecting pool, maximize your affiliate program by working with the best and leaving the rest. As the old 80/20 adage implies, most of your revenue will come from a very small percentage of your affiliates. Because it can be time-consuming to manage a larger affiliate network, consider selecting only a few companies initially, and interview them before signing them on. Affiliates are an extension of your sales force and represent your online brand, so choose partners carefully.
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