Just like ClickBank, Commission Junction is an advertising platform that works with suppliers. Commission Junction works with big brand names. But they are still a middleman. You won’t be working or dealing with the individual companies yourself, which can be nice and can be a pain. Commission Junction does have higher requirements for joining their program. It’s not impossible if you’re serious about affiliate marketing.
You should also make sure you aren't competing with your own affiliates for eyeballs. Any marketing channels you're using, such as search engines, content sites or e-mail lists, should be off limits to your affiliates. Put marketing restrictions into your affiliate agreement and notify partners immediately. It's your program--you set the rules. Or, if you prefer, you can let your affiliates run the majority of your internet marketing.